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2016

Burkett PR, Kuchroo VK. IL-17 Blockade in Psoriasis. Cell. 2016 Dec 15;167(7):1669. doi: 10.1016/j.cell.2016.11.044. PubMed PMID: 27984714.

Kishi Y, Kondo T, Xiao S, Yosef N, Gaublomme J, Wu C, Wang C, Chihara N, Regev A, Joller N, Kuchroo VK. Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity. J Exp Med. 2016 Oct 17;213(11):2489-2501. Epub 2016 Sep 26. PubMed PMID: 27670590; PubMed Central PMCID: PMC5068226.

Suzuki E, Maverakis E, Sarin R, Bouchareychas L, Kuchroo VK, Nestle FO, Adamopoulos IE. T Cell-Independent Mechanisms Associated with Neutrophil Extracellular Trap Formation and Selective Autophagy in IL-17A-Mediated Epidermal Hyperplasia. J Immunol. 2016 Dec 1;197(11):4403-4412. Epub 2016 Oct 24.PubMed PMID: 27798153; PubMed Central PMCID: PMC5123839.

Sage PT, Ron-Harel N, Juneja VR, Sen DR, Maleri S, Sungnak W, Kuchroo VK, Haining WN, Chevrier N, Haigis M, Sharpe AH. Suppression by T(FR) cells leads to durable and selective inhibition of B cell effector function. Nat Immunol. 2016 Dec;17(12):1436-1446. doi: 10.1038/ni.3578. Epub 2016 Oct 3. PubMed PMID:27695002.

Singer M, Wang C, Cong L, Marjanovic ND, Kowalczyk MS, Zhang H, Nyman J, Sakuishi K, Kurtulus S, Gennert D, Xia J, Kwon JY, Nevin J, Herbst RH, Yanai I,Rozenblatt-Rosen O, Kuchroo VK, Regev A, Anderson AC. A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells. Cell. 2016 Sep 8;166(6):1500-1511.e9. doi: 10.1016/j.cell.2016.08.052. PubMed PMID:27610572; PubMed Central PMCID: PMC5019125.

Yoon J, Leyva-Castillo JM, Wang G, Galand C, Oyoshi MK, Kumar L, Hoff S, He R,Chervonsky A, Oppenheim JJ, Kuchroo VK, van den Brink MR, Malefyt Rde W, Tessier PA, Fuhlbrigge R, Rosenstiel P, Terhorst C, Murphy G, Geha RS. IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization. J Exp Med. 2016 Sep 19;213(10):2147-66. doi:10.1084/jem.20150376. Epub 2016 Aug 22. PubMed PMID: 27551155; PubMed Central PMCID: PMC5032726.

Meyer Zu Horste G, Wu C, Wang C, Cong L, Pawlak M, Lee Y, Elyaman W, Xiao S, Regev A, Kuchroo VK. RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression. Cell Rep. 2016 Jul 12;16(2):392-404. doi:10.1016/j.celrep.2016.05.088. Epub 2016 Jun 23. PubMed PMID: 27346359; PubMed Central PMCID: PMC4984261.

Shim H, Wu C, Ramsamooj S, Bosch KN, Chen Z, Emerling BM, Yun J, Liu H, Choo-Wing R, Yang Z, Wulf GM, Kuchroo VK, Cantley LC. Deletion of the gene Pip4k2c, a novel phosphatidylinositol kinase, results in hyperactivation of the immune system. Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7596-601. doi:10.1073/pnas.1600934113. Epub 2016 Jun 16. PubMed PMID: 27313209; PubMed Central PMCID: PMC4941458.

Anderson AC, Joller N, Kuchroo VK. Lag-3, Tim-3, and TIGIT: Co-inhibitoryReceptors with Specialized Functions in Immune Regulation. Immunity. 2016 May17;44(5):989-1004. doi: 10.1016/j.immuni.2016.05.001. Review. PubMed PMID:27192565; PubMed Central PMCID: PMC4942846.

Chihara N, Madi A, Karwacz K, Awasthi A, Kuchroo VK. Differentiation andCharacterization of Tr1 Cells. Curr Protoc Immunol. 2016 Apr1;113:3.27.1-3.27.10. doi: 10.1002/0471142735.im0327s113. PubMed PMID: 27038462.

Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK,Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS. Corrigendum: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature. 2016 Aug 18;536(7616):359. doi: 10.1038/nature17421. Epub 2016 Mar 16. PubMed PMID: 26982724; PubMed Central PMCID: PMC5110397.

Jayaraman P, Jacques MK, Zhu C, Steblenko KM, Stowell BL, Madi A, Anderson AC,Kuchroo VK, Behar SM. TIM3 Mediates T Cell Exhaustion during Mycobacteriumtuberculosis Infection. PLoS Pathog. 2016 Mar 11;12(3):e1005490. doi:10.1371/journal.ppat.1005490. eCollection 2016 Mar. PubMed PMID: 26967901; PubMed Central PMCID: PMC4788425.

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