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2008

Strandberg L, Ambrosi A, Espinosa A, Ottosson L, Eloranta ML, Zhou W, Elfving A, Greenfield E, Kuchroo VK, Wahren-Herlenius M. Interferon-alpha Induces Up-regulation and Nuclear Translocation of the Ro52 Autoantigen as Detected by a Panel of Novel Ro52-specific Monoclonal Antibodies. J Clin Immunol. 2008; 28:220-31

Degauque N, Mariat C, Kenny J, Zhang D, Gao W, Vu MD, Alexopoulos S, Oukka M, Umetsu DT, DeKruyff RH, Kuchroo V, Zheng XX, Strom TB. Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice. J Clin Invest. 2008 Feb; 118(2): 735-41. PMCID: PMC2129234

Seki M, Oomizu S, Sakata KM, Sakata A, Arikawa T, Watanabe K, Ito K, Takeshita K, Niki T, Saita N, Nishi N, Yamauchi A, Katoh S, Matsukawa A, Kuchroo V, Hirashima M. Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis. Clin Immunol. 2008 Apr;127(1):78-88.

Rodriguez-Manzanet R, Meyers JH, Balasubramanian S, Slavik J, Kassam N, Dardalhon V. , Greenfield EA, Anderson AC, Sobel RA, Hafler DA, Strom TB, Kuchroo VK. TIM-4 Expressed on APCs Induces T Cell Expansion and Survival. J Immunol. 2008 Apr 1;180(7):4706-4713. Accepted for publication Jan 2008. PMCID: PMC2948965

Tzianabos AO, Holsti MA, Zheng XX, Stucchi AF, Kuchroo VK, Strom TB, Glimcher LH, Cruikshank WW. Functional Th1 cells are required for surgical adhesion formation in a murine model. J Immunol. 2008 May 15;180(10):6970-6. Accepted for publication Mar 2008.

Chen ML, Yan BS, Bando Y, Kuchroo VK, Weiner HL. Latency-Associated Peptide Identifies a Novel CD4+CD25+ Regulatory T Cell Subset with TGF{beta}-Mediated Function and Enhanced Suppression of Experimental Autoimmune Encephalomyelitis. J Immunol. 2008 Jun 1;180(11):7327-37. Accepted for publication Mar 2008.

Yang L, Anderson DE, Baecher-Allan C, Hastings WD, Bettelli E, Oukka M, Kuchroo VK, Hafler DA. IL-21 and TGF-beta are required for differentiation of human T(H)17 cells. Nature. 2008 Jul 17; 454:350-2. PMCID: PMC2760130

Elyaman W, Kivisäkk P, Reddy J, Chitnis T, Raddassi K, Imitola J, Bradshaw E, Kuchroo VK, Yagita H, Sayegh MH, Khoury SJ. Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis. Am J Pathol. 2008 Aug; 173(2): 411-22. PMCID: PMC2475778

Laouar Y, Town T, Jeng D, Tran E, Wan Y, Kuchroo VK, Flavell. TGF-beta signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis. Proc Natl Acad Sci USA. 2008 Aug 5; 105(31): 10865-70. PMCID: PMC2504840

Xiao S, Jin H, Korn T, Kiu SM, Oukka M, Lim B, Kuchroo VK. Retinoic acid increases Fox-3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression. J Immunol. 2008 Aug 15; 181(4): 2277-84. PMCID: PMC2722959

Dardalhon V, Awasthi A, Kwon H, Galileos G, Gao W, Sobel RA, Mitsdoerffer M, Strom TB, Elyaman W, Ho I-C, Khoury S, Oukka M, Kuchroo VK. IL-4 inhibits TGF-b-induced-Foxp3+ T cells and generates a Foxp3 effector T cells. Nat Immunol. 2008. Dec; 9(12): 1347-55. PMCID: PMC2999006

Korn T, Mitsdoerffer M, Croxford AL, Awasthi A, Dardalhon VA, Galileos G, Vollmar P, Stritesky GL, Kaplan MH, Waisman A, Kuchroo VK, Oukka M. IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells. Proc Natl Acad Sci USA. 2008 Nov 25;105(47): 18460-5. PMCID: PMC2587589

Dardalhon V, Korn T, Kuchroo VK, Anderson AC. Role of Th1 and Th17 cells in organs-specific autoimmunity. J Autoimmun. 2008 Nov; 31(3): 252-6. PMCID: PMC3178062

Anderson AC, Chandwaskar R, Lee DH, Kuchroo VK. Cutting edge: the Idd3 genetic interval determines regulatory T cell function through CD11b+CD11c- APC. J Immunol 2008 Dec 1;181(11): 7449-52. PMCID: PMC2614216

Nagahara K, Arikawa T, Oomizu S, Kontani K, Nobumoto A, Tateno H, Watanabe K, Niki T, Katoh S, Miyake M, Nagahata S, Hirabayashi J, Kuchroo VK, Yamauchi A, Hirashima M. Galetctin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions. J Immunol 2008 Dec 1; 181(11): 7660-9.

Hafler JP, Maier LM, Copper JD, Plagnol V, Hinks A, Simmonds MJ, Stevens HE, Walker NM, Healy B, Howson JM, Maisuria M, Duley S, Coleman G, Gough SC, The International Multiple Sclerosis Genetics Consortium (IMSGC), Worthington J, Kuchroo VK, Wicker LS, Todd JA. CD226 Gly307Ser association with multiple autoimmune diseases. Genes Immun. 2009 Jan; 10(1):5-10. Epub 2008 Oct 30. PMCID: PMC2635550

Bauquet AT, Jin H, Paterson AM, Mitsdoerffer M, Ho I-C, Sharpe AH, Kuchroo VK. The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells TH17 cells. Nat Immunol. 2009 Feb;10(2):167-75. Epub 2008 Dec 21. PMCID: PMC2742982

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