2017

2017

 

A-Gonzalez N, Quintana JA, García-Silva S, Mazariegos M, González de la Aleja A, Nicolás-Ávila JA, Walter W, Adrover JM, Crainiciuc G, Kuchroo VK, Rothlin CV, Peinado H, Castrillo A, Ricote M, Hidalgo A. Phagocytosis imprints heterogeneity in tissue-resident macrophages. J Exp Med. 2017 May 1;214(5):1281-1296. doi:10.1084/jem.20161375. Epub 2017 Apr 21. PubMed PMID: 28432199; PubMed Central PMCID: PMC5413334.

 

Das M, Zhu C, Kuchroo VK. Tim-3 and its role in regulating anti-tumorimmunity. Immunol Rev. 2017 Mar;276(1):97-111. doi: 10.1111/imr.12520. Review.PubMed PMID: 28258697.

 

Karwacz K, Miraldi ER, Pokrovskii M, Madi A, Yosef N, Wortman I, Chen X, Watters A, Carriero N, Awasthi A, Regev A, Bonneau R, Littman D, Kuchroo VK. Critical role of IRF1 and BATF in forming chromatin landscape during type 1 regulatory cell differentiation. Nat Immunol. 2017 Apr;18(4):412-421. doi: 10.1038/ni.3683. Epub 2017 Feb 6. PubMed PMID: 28166218.

 

Wu C, Chen Z, Dardalhon V, Xiao S, Thalhamer T, Liao M, Madi A, Franca RF, HanT, Oukka M, Kuchroo V. The transcription factor musculin promotes the unidirectional development of peripheral T(reg) cells by suppressing the T(H)2 transcriptional program. Nat Immunol. 2017 Mar;18(3):344-353. doi: 10.1038/ni.3667. Epub 2017 Jan 23. PubMed PMID: 28114290.

 

Brauner S, Folkersen L, Kvarnström M, Meisgen S, Petersen S, Franzén-Malmros M, Mofors J, Brokstad KA, Klareskog L, Jonsson R, Westerberg LS, Trollmo C, Malmström V, Ambrosi A, Kuchroo VK, Nordmark G, Wahren-Herlenius M. H1N1 vaccination in Sjögren’s syndrome triggers polyclonal B cell activation and promotes autoantibody production. Ann Rheum Dis. 2017 Oct;76(10):1755-1763. doi: 10.1136/annrheumdis-2016-210509. Epub 2017 Jul 31. PubMed PMID: 28760805; PubMed Central PMCID: PMC5629946.

 

Gabriely G, da Cunha AP, Rezende RM, Kenyon B, Madi A, Vandeventer T, Skillin N, Rubino S, Garo L, Mazzola MA, Kolypetri P, Lanser AJ, Moreira T, Faria AMC, Lassmann H, Kuchroo V, Murugaiyan G, Weiner HL. Targeting latency-associated peptide promotes antitumor immunity. Sci Immunol. 2017 May 19;2(11). pii: eaaj1738. doi: 10.1126/sciimmunol.aaj1738. PubMed PMID: 28763794; PubMed Central PMCID: PMC5657397.

 

Ding Q, Mohib K, Kuchroo VK, Rothstein DM. TIM-4 Identifies IFN-γ-Expressing Proinflammatory B Effector 1 Cells That Promote Tumor and Allograft Rejection. J Immunol. 2017 Oct 1;199(7):2585-2595. doi: 10.4049/jimmunol.1602107. Epub 2017 Aug 28. PubMed PMID: 28848066; PubMed Central PMCID: PMC5726915.

 

Nylander AN, Ponath GD, Axisa PP, Mubarak M, Tomayko M, Kuchroo VK, Pitt D, Hafler DA. Podoplanin is a negative regulator of Th17 inflammation. JCI Insight.  2017 Sep 7;2(17). pii: 92321. doi: 10.1172/jci.insight.92321. PubMed PMID: 28878118; PubMed Central PMCID: PMC5621890.

 

Joller N, Kuchroo VK. Tim-3, Lag-3, and TIGIT. Curr Top Microbiol Immunol. 2017;410:127-156. doi: 10.1007/82_2017_62. PubMed PMID: 28900677; PubMed Central PMCID: PMC5902028.

 

Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour RE, Nyman J, Dionne D, Hofree M, Cuoco MS, Rodman C, Farouq D, Haas BJ, Tickle TL, Trombetta JJ, Baral P, Klose CSN, Mahlakõiv T, Artis D, Rozenblatt-Rosen O, Chiu IM, Levy BD, Kowalczyk MS, Regev A, Kuchroo VK. The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation. Nature. 2017 Sep 21;549(7672):351-356.doi: 10.1038/nature24029.Epub 2017 Sep 13. Erratum in: Nature. 2017 Nov 15;:. PubMed PMID: 28902842;PubMed Central PMCID: PMC5746044.

 

Jacquelot N, Roberti MP, Enot DP, Rusakiewicz S, Ternès N, Jegou S, Woods DM, Sodré AL, Hansen M, Meirow Y, Sade-Feldman M, Burra A, Kwek SS, Flament C,Messaoudene M, Duong CPM, Chen L, Kwon BS, Anderson AC, Kuchroo VK, Weide B,Aubin F, Borg C, Dalle S, Beatrix O, Ayyoub M, Balme B, Tomasic G, Di Giacomo AM, Maio M, Schadendorf D, Melero I, Dréno B, Khammari A, Dummer R, Levesque M,Koguchi Y, Fong L, Lotem M, Baniyash M, Schmidt H, Svane IM, Kroemer G,Marabelle A, Michiels S, Cavalcanti A, Smyth MJ, Weber JS, Eggermont AM, Zitvogel L.Predictors of responses to immune checkpoint blockade in advanced melanoma. Nat Commun. 2017 Sep 19;8(1):592. doi: 10.1038/s41467-017-00608-2. PubMed PMID: 28928380; PubMed Central PMCID: PMC5605517.

 

Singer M, Wang C, Cong L, Marjanovic ND, Kowalczyk MS, Zhang H, Nyman J,Sakuishi K, Kurtulus S, Gennert D, Xia J, Kwon JYH, Nevin J, Herbst RH, Yanai I, Rozenblatt-Rosen O, Kuchroo VK, Regev A, Anderson AC. A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells. Cell. 2016 Sep 8;166(6):1500-1511.e9. doi: 10.1016/j.cell.2016.08.052. Erratum in: Cell.2017 Nov 16;171(5):1221-1223. PubMed PMID: 27610572; PubMed Central PMCID:PMC5019125.

 

Hu D, Notarbartolo S, Croonenborghs T, Patel B, Cialic R, Yang TH, Aschenbrenner D, Andersson KM, Gattorno M, Pham M, Kivisakk P, Pierre IV, Lee Y, Kiani K, Bokarewa M, Tjon E, Pochet N, Sallusto F, Kuchroo VK, Weiner HL.Transcriptional signature of human pro-inflammatory T(H)17 cells identifiesreduced IL10 gene expression in multiple sclerosis. Nat Commun. 2017 Nov17;8(1):1600. doi: 10.1038/s41467-017-01571-8. PubMed PMID: 29150604; PubMedCentral PMCID: PMC5693957.